Award
National Cancer Institute 3U01CA282114-03S1
Spatial functional genomics to identify regulators of the tumor microenvironment and cancer immunity
Recipient
I.C.A.H.N. School of Medicine at Mount Sinai, NY, USA
Award Amount
$100,528.00
Ceiling
$100,528.00
Awarded
September 16, 2025
Identifier
3U01CA282114-03S1
Award for research on spatial functional genomics to identify tumor microenvironment regulators and cancer immunity, focusing on four cancer types using advanced genomic and computational methods.
Description
The project aims to determine genes regulating tumor composition and facilitating tumor growth and resistance to immunity & immunotherapy. Focus on four cancers: NSCLC, PDAC, HGSOC, and OSCC. Utilizes large-scale genomic and transcriptomic data, spatial functional genomics, and computational analysis. Employs a spatial functional genomics platform called Perturb-map. Study in immunocompetent, orthotopic models. Outcomes include insights into tumor behavior and treatment resistance, aiding personalized medicine.