Award

National Institute of General Medical Sciences 5R35GM151104-03

Rapid Assessment of Proteoform-Resolved Higher-Order Structures

Recipient

University of Nevada Reno

Award Amount

$359,248.00

Ceiling

$359,248.00

Awarded

September 20, 2023

Identifier

5R35GM151104-03

Award to University of Nevada Reno by National Institute of General Medical Sciences for research on proteoform-resolved higher-order structures using advanced mass spectrometry techniques, funded at $359,248.

Description

The project aims to develop techniques to profile post-translational modifications (PTMs) and their regulation of protein function. The research involves mass spectrometry, top-down proteomics, ion mobility spectrometry, chemical derivatization, and collision-induced unfolding. The project is funded by NIH grant PAR-20-117. The award amount is $359,248, with a budget period from August 1, 2025, to July 31, 2026. The project start date is September 20, 2023, and end date is July 31, 2028. The primary organization is the University of Nevada Reno, located in Reno, NV. The project is related to translational research in biomedical sciences.

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