Award
Johns Hopkins University 1R01DE035882-01
Mechanisms of XIST-TLR7 Signaling in Sjogren's Disease
Recipient
Johns Hopkins University
Award Amount
$464,180.00
Ceiling
$464,180.00
Awarded
August 04, 2026
Identifier
1R01DE035882-01
Research grant awarded to study XIST-TLR7 signaling mechanisms in Sjogren's Disease, targeting autoimmune disease pathways and potential therapies.
Description
This is a research grant focused on the mechanisms of XIST-TLR7 signaling in Sjogren's Disease, with a focus on autoimmune disease mechanisms, biomarker identification, and potential therapeutic approaches. The project involves analysis of XIST expression, mechanisms of release into extracellular vesicles, and regulation in mature tissues.