Award
NIH Reporter #5R61CA291117-02
Evolved Molecules that Destroy Cancer Relevant Proteins
Recipient
Not specified
Award Amount
$215,564.00
Ceiling
$215,564.00
Awarded
September 10, 2025
Identifier
5R61CA291117-02
Award for developing evolved molecules to target and destroy cancer-relevant proteins using advanced laboratory techniques, funded by the National Cancer Institute.
Description
The project involves developing reagents that can bind and cleave target proteins, with applications in cancer diagnostics and therapy. The project aims to create AEGISbodies and AEGISCleavers using laboratory in vitro evolution (LIVE) techniques, focusing on targeting proteins such as Programmed Death-Ligand 1 (PD-L1).