Award
NIH Reporter #5R03HL171434-02
Host immunity in the lung is determined by the enhanced utilization of glucose by multi-drug resistant Klebsiella pneumoniae
Recipient
Columbia University Health Sciences
Award Amount
$123,375.00
Ceiling
$123,375.00
Awarded
December 17, 2024
Identifier
5R03HL171434-02
Research project funded by the National Heart Lung and Blood Institute to study the impact of glucose utilization by multi-drug resistant Klebsiella pneumoniae on lung immunity in ventilator-dependent children, aiming to improve health outcomes.
Description
This project investigates how lung immunity is affected by bacterial consumption of glucose, focusing on multi-drug resistant Klebsiella pneumoniae in ventilator-dependent pediatric patients. The research aims to understand the metabolic environment's role in bacterial persistence and impaired lung function, with potential translational impacts on improving ventilator-dependent children's health.