Award
NIH Reporter #5R35GM153190-03
Post-transcription Initiation Control of Gene Expression
Recipient
Pennsylvania State University, The, University Park, PA, USA
Award Amount
$456,521.00
Ceiling
$456,521.00
Awarded
September 03, 2026
Identifier
5R35GM153190-03
This NIH grant supports research on gene expression regulation mechanisms involving RNA polymerase pausing and transcription termination in bacteria, aiming to improve understanding of gene regulation relevant to human health.
Description
Insight into gene regulatory mechanisms will be sought through studies of RNA polymerase pausing, transcription termination, translation control, and RNA binding proteins in Bacillus subtilis and Escherichia coli. Proper regulation of gene expression is of paramount importance for the function of cells in all organisms. As several human diseases arise in part through inappropriate gene expression, these studies will contribute to improving human health by providing a detailed mechanistic understanding of how genes are regulated.