Award
NIH Reporter #1RF1AG094856-01
Inhibition of Abeta42 aggregation by helix stabilizing peptidomimetic biomaterials
Recipient
Not specified
Award Amount
$3,297,926.00
Ceiling
$3,297,926.00
Awarded
August 26, 2025
Identifier
1RF1AG094856-01
Award for developing biomaterials to inhibit Abeta42 aggregation, targeting Alzheimer's disease treatment through design and testing of peptidic foldamers and molecular probes.
Description
This project aims to develop biomaterials targeting amyloid beta (A f) structures to prevent and disrupt aggregation, with potential applications in Alzheimer's disease treatment. The project involves designing helical peptidic foldamers, conducting in vitro and in vivo assays, and developing molecular probes and therapeutic agents.