Award
NIH Reporter #4R01CA291644-03
Novel applications and translation of [18F]hGTS13, a system xc- specific radiopharmaceutical
Recipient
Stanford University, Department of Radiation-Diagnostic/Oncology
Award Amount
$1,194,464.00
Ceiling
$1,194,464.00
Awarded
June 19, 2026
Identifier
4R01CA291644-03
Development and translation of [18F]hGTS13 radiotracer for cancer imaging to assess ferroptosis sensitivity and monitor therapy, led by Stanford University under NIH funding.
Description
This project aims to test the hypothesis that [18F]hGTS13, a system xc- specific radiotracer, can inform on the sensitivity of different cancers to ferroptosis and monitor pharmacological induction of ferroptosis. The project will also translate [18F]hGTS13 for first-in-human investigation. It involves developing and translating a novel radiotracer for cancer imaging, focusing on ferroptosis mechanisms, with potential clinical applications in patient selection and therapy monitoring.