Award
National Institute of Allergy and Infectious Diseases 5R01AI175941-04
Defining correlates of protection from dengue illness in a long-term cohort study of multigenerational households in Thailand
Recipient
Upstate Medical University, Syracuse, NY, United States
Award Amount
$427,769.00
Ceiling
$427,769.00
Awarded
July 02, 2026
Identifier
5R01AI175941-04
A research project studying immune responses to dengue virus in a long-term cohort in Thailand to identify immune correlates of protection against dengue illness.
Description
This study leverages a long-term family cohort study for dengue virus (DENV) in Thailand to define how early immune environment and exposures shape future antibody-mediated immune profiles and risks of dengue illness. The research aims to identify features of exposure histories and pre-infection immunity associated with protection from dengue illness, supporting the identification of correlates of protection for public health surveillance and countermeasure development.