Award
NIH Reporter #11218663
Cellular Mechanisms of Acute-Intermittent Hypercapnic-Hypoxia Induced Phrenic Motor Plasticity
Recipient
National Heart Lung and Blood Institute (NHLBI)
Award Amount
$75,520.00
Ceiling
$75,520.00
Awarded
August 29, 2025
Identifier
11218663
Award for research on neural plasticity related to breathing control, focusing on phrenic motor plasticity induced by acute intermittent hypoxia, funded by NHLBI with $75,520 for FY 2025.
Description
This project focuses on the neural plasticity related to breathing control, specifically phrenic long-term facilitation (pLTF) following acute intermittent hypoxia (AIH). The research aims to uncover mechanisms behind enhanced pLTF induced by AIHH compared to AIH, with hypotheses involving carotid chemoreceptor activation and spinal blood flow during hypoxia. The project is funded by the National Heart Lung and Blood Institute (NHLBI) under the NIH, with a budget of $75,520 for FY 2025, spanning from September 13, 2025, to September 12, 2026. The project is part of a broader effort to improve respiratory and motor functions in clinical populations such as those with spinal cord injuries and ALS.