Award
NIH Reporter #5R35GM158085-02
Analysis of active genetic elements in germline and somatic cell lineages
Recipient
University of California, San Diego
Award Amount
$672,000.00
Ceiling
$672,000.00
Awarded
August 05, 2026
Identifier
5R35GM158085-02
This award supports research on CRISPR-based gene-drive systems to block malaria transmission and explore gene therapy strategies using homologous chromosome repair mechanisms.
Description
Development and analysis of novel CRISPR-based gene-drive and allelic-drive systems in germline and somatic cells to advance next-generation germline drive systems and dissect mechanistic basis for Cas9 versus Nickases activities for potential gene therapy strategies.