Award
NIH Reporter #PA-25-426
Orai1-dependent calcium signaling in microglia within the prelimbic cortex regulates binge-like alcohol consumption via cytokine-mediated disruption of neural processing
Recipient
Northwestern University, Chicago, IL
Award Amount
$52,143.00
Ceiling
$52,143.00
Awarded
August 27, 2026
Identifier
PA-25-426
Research project funded by NIAAA to study microglial calcium signaling's role in binge drinking and AUD, aiming to find new therapeutic targets.
Description
This research aims to identify how immune signaling in the brain contributes to binge drinking, a major risk factor for Alcohol Use Disorder (AUD). It focuses on microglial calcium signaling and its role in disrupting neural circuits, with the goal of revealing new therapeutic targets to reduce harmful alcohol use.