Award
National Institutes of Health 5R01CA262903-05
The Role of YY1 in Castration-Resistant Prostate Cancer
Recipient
Duke University
Award Amount
$403,094.00
Ceiling
$403,094.00
Awarded
August 18, 2025
Identifier
5R01CA262903-05
The award supports research on the role of the YY1 transcription factor in castration-resistant prostate cancer (CRPC), focusing on its interaction with AR-V7 and metabolic gene regulation to understand therapy resistance and identify new treatment strategies.
Description
This project aims to elucidate the role of YY1 in CRPC progression and resistance, with potential therapeutic implications targeting YY1 and its co-activators.