Award
NIH Reporter #1R01NS150256-01
Paired Stimulation Plasticity for Motor Recovery
Recipient
University of Newcastle, Newcastle upon Tyne, United Kingdom
Award Amount
$367,075.00
Ceiling
$367,075.00
Awarded
September 03, 2026
Identifier
1R01NS150256-01
A NIH grant project investigating paired neural stimulation to enhance motor recovery in spinal cord injury patients by studying neural plasticity mechanisms and developing optimized stimulation protocols.
Description
This project aims to reveal fundamental principles underlying how paired stimulation can change connections within the parts of the brain which control movement. The research will focus on understanding the mechanisms of action of protocols like Spinal Paired Associative Stimulation (Spinal PAS) and Startle, which act on corticospinal and cortico-reticulospinal systems respectively. The goal is to develop optimized stimulation protocols to enhance neural plasticity and facilitate motor recovery, especially in patients with spinal cord injury.