Award
NIH Reporter #4R01AG079519-02
Cerebrovascular contributions to Alzheimer's disease in adults with Down Syndrome
Recipient
Columbia University Health Sciences, New York, NY
Award Amount
$1,008,629.00
Ceiling
$1,008,629.00
Awarded
August 19, 2026
Identifier
4R01AG079519-02
A longitudinal cohort study funded by NIH to analyze cerebrovascular disease markers in adults with Down syndrome to understand their role in Alzheimer's disease and inform treatment strategies.
Description
This project examines neuroimaging, blood-based, and neuropathological markers of vascular contributions to cognitive impairment and Alzheimer's disease (AD) in adults with Down syndrome (DS). It aims to identify potential targets to mitigate public health crises in this population and inform interventions in the neurotypical population.