Award
NIH Reporter #11398121
Molecular basis for functional S1PR1 antagonists in the treatment of comorbid migraine and temporomandibular disorders
Recipient
University of Maryland Baltimore
Award Amount
$573,560.00
Ceiling
$573,560.00
Awarded
September 08, 2026
Identifier
11398121
Award for research on S1PR1 antagonists targeting migraine and temporomandibular disorders, funded by NINDS/NIH, with a total amount of approximately $573,560 over five years.
Description
The project focuses on the molecular mechanisms of migraine and temporomandibular disorders, targeting S1PR1 signaling. It involves multidisciplinary approaches including behavioral studies, molecular pharmacology, electrophysiology, genetics, biochemistry, immunohistochemistry, and mass spectrometry. The project aims to validate S1PR1 as a therapeutic target for comorbid migraine and TMD. The project duration is from September 1, 2024, to August 31, 2029.