Award
NIH Reporter #1R01HL180294-01
Excess cardiovascular inflammation in TB and HIV: EXFIN-TB
Recipient
UNIVERSITY OF PENNSYLVANIA
Award Amount
$2,513,201.00
Ceiling
$2,513,201.00
Awarded
August 29, 2025
Identifier
1R01HL180294-01
Award for a research project studying cardiovascular inflammation in TB and HIV patients to improve treatment strategies and reduce cardiovascular risks.
Description
This project aims to characterize clinical risk factors and inflammatory pathways associated with subclinical cardiovascular disease in people treated for TB, to inform future treatment strategies to prevent or reduce long-term cardiovascular morbidity and mortality among TB survivors. It involves a prospective cohort study leveraging ongoing research, with a focus on TB and HIV coinfection, arterial stiffness, and inflammasome activity.