Award
National Cancer Institute 5R01CA290541-03
Alternative Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
Recipient
University of Pennsylvania, Philadelphia, PA
Award Amount
$650,125.00
Ceiling
$650,125.00
Awarded
April 21, 2026
Identifier
5R01CA290541-03
Research project funded by the National Cancer Institute to study the potential of electronic nicotine delivery systems as harm reduction tools for persistent cigarette smokers through a randomized trial.
Description
The project aims to investigate the substitutability of electronic cigarettes (ECIGS) versus oral nicotine pouches (ONPS) for combustible cigarette smoking among persistent smokers. It will assess factors influencing switching and the potential harm reduction benefits. The study involves a longitudinal, randomized trial with 200 participants, baseline assessments, laboratory visits, and follow-up over 26 weeks.