Award
University of Massachusetts 11360649
Investigating siRNA-mediated inhibition of ischemia-reperfusion injury during the liver transplantation process
Recipient
UNIV OF MASSACHUSETTS MED SCH WORCESTER
Award Amount
$52,007.00
Ceiling
$52,007.00
Awarded
June 29, 2026
Identifier
11360649
Research project focused on using siRNA technology to reduce ischemia-reperfusion injury in liver transplants, aiming to improve donor availability and patient outcomes.
Description
The project involves using GalNAc-siRNA technology to inhibit Fas and other mediators of ischemia-reperfusion injury in liver transplantation. The project aims to develop in vivo and ex vivo approaches to increase the donor pool and improve patient survival.