Award
National Institute on Drug Abuse 5K01DA056854-04
Involvement of dopamine signaling in chronic pain-induced negative affective state and nicotine use comorbidity
Recipient
Yale University
Award Amount
$194,429.00
Ceiling
$194,429.00
Awarded
March 26, 2026
Identifier
5K01DA056854-04
This NIH-funded research project at Yale University studies how chronic pain affects dopamine signaling leading to increased nicotine use, aiming to develop therapeutic interventions.
Description
Research project investigating the neurobiological mechanism where chronic pain decreases mesolimbic dopaminergic signaling, inducing a negative affective state and increasing nicotine use, modeled in rats to develop interventions for co-morbid pain and nicotine addiction.