Award
National Institute on Alcohol Abuse and Alcoholism 1R21AA030221-01A1
Effects of binge ethanol on neuroinflammation and neurodegeneration with high fat diets
Recipient
Seton Hall University
Award Amount
$391,903.00
Ceiling
$391,903.00
Awarded
August 03, 2023
Identifier
1R21AA030221-01A1
The award funds research on how binge ethanol consumption affects neuroinflammation and neurodegeneration in mice on high-fat diets, exploring the potential protective effects of n-3 polyunsaturated fatty acids.
Description
This project investigates the effects of binge ethanol on neuroinflammation and neurodegeneration in the context of high-fat diets, with a focus on the potential mitigating role of n-3 PUFAs like DHA. The research involves cellular and molecular analyses, including immunofluorescence and RNA sequencing, to understand the interaction between alcohol consumption, diet, and neurodegenerative processes.