Award
NIH Reporter #4R37CA261987-06
Targeting Wnt signaling in therapy-resistant ovarian cancer
Recipient
University of Colorado Denver, Aurora, CO
Award Amount
$384,824.00
Ceiling
$384,824.00
Awarded
July 08, 2026
Identifier
4R37CA261987-06
This NIH/NCI funded project investigates overcoming PARP inhibitor resistance in ovarian cancer by targeting Wnt/beta-catenin signaling to enhance immune activation and reduce tumor progression.
Description
Research project funded by NIH/NCI to study the role of Wnt signaling in PARP inhibitor-resistant ovarian cancer and to develop alternative therapeutic strategies combining Wnt inhibition with PARP inhibitors and CCL2 targeting.