Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK136904-03
A Pilot Study to Evaluate the Anabolic Effect of Testosterone on Muscles of the Pelvic Floor in Older Women with Stress Urinary Incontinence
Recipient
Brigham and Women's Hospital
Award Amount
$354,840.00
Ceiling
$354,840.00
Awarded
July 03, 2025
Identifier
5R01DK136904-03
This study investigates whether testosterone therapy can increase pelvic floor muscle mass and improve urinary function in older women with stress urinary incontinence. The trial will measure pelvic floor muscle volume via MRI, urodynamic function, urinary symptoms, and quality of life over 12 weeks.
Description
A randomized, double-blind, placebo-controlled proof-of-concept trial in older postmenopausal women with stress urinary incontinence to assess whether testosterone therapy can increase pelvic floor muscles and improve urinary function.