Award
NIH Reporter #4R37CA255245-06
Targeting vulnerabilities of PPM1D-mutant gliomas
Recipient
Dana-Farber Cancer Inst, Boston, MA, United States
Award Amount
$404,055.00
Ceiling
$404,055.00
Awarded
March 23, 2026
Identifier
4R37CA255245-06
Research project funded by the National Cancer Institute to study PPM1D mutations in gliomas and identify therapeutic targets.
Description
This project aims to dissect the mechanisms through which PPM1D mutations induce tumor formation and identify vulnerabilities for therapeutic targeting in diffuse midline gliomas (DMGs) and other PPM1D-mutant tumors.