Award
National Cancer Institute 5R01CA294640-02
Homologous recombination repair pathway mutations and genetic mechanisms shaping anti-tumor immunity and immunotherapy efficacy
Recipient
CLEVELAND CLINIC LERNER COM-CWRU
Award Amount
$698,349.00
Ceiling
$698,349.00
Awarded
July 24, 2026
Identifier
5R01CA294640-02
NIH grant awarded by the National Cancer Institute to study homologous recombination repair pathway mutations and their impact on anti-tumor immunity and immunotherapy efficacy, with a budget of $698,349.
Description
This NIH grant supports research on the effects of homologous recombination deficiency on tumor immunity and immunotherapy. The project involves mechanistic studies in murine models, analysis of human tumor samples, and investigation of resistance mechanisms. Funded by the National Cancer Institute with a total budget of approximately $698,349 for fiscal year 2026.