Award
National Institute of Neurological Disorders and Stroke 1R01NS147100-01
Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 onset ME/CFS versus Pre-Pandemic ME/CFS Patients
Recipient
Johns Hopkins University, Baltimore, MD
Award Amount
$633,378.00
Ceiling
$633,378.00
Awarded
April 17, 2026
Identifier
1R01NS147100-01
Research project funded by NINDS to investigate blood-brain barrier integrity and immune dynamics in ME/CFS patients with pre- and post-pandemic onset, aiming to understand neuroinflammation's role in cognitive and mood impairments.
Description
This project studies the disruption of blood-brain barrier integrity and immune cell migration contributing to neuroinflammation and neuropsychiatric burden in ME/CFS patients, comparing pre-pandemic and post-SARS-CoV-2 onset cases, using brain imaging, neuropsychiatric assessments, and immune signatures.