Award
National Institute of Neurological Disorders and Stroke 5R01NS089737-12
The Role of Abnormal Inter-Organelle Communication in the Pathogenesis of Tauopathy
Recipient
Rutgers, The State University of New Jersey
Award Amount
$565,089.00
Ceiling
$565,089.00
Awarded
February 26, 2026
Identifier
5R01NS089737-12
This project studies how defects in autophagosome-mitochondria interactions contribute to tauopathies like Alzheimer's disease, aiming to find new therapeutic targets by understanding TBC1D15's role.
Description
The study investigates the role of autophagosome-mitochondria contact defects in tauopathy, focusing on TBC1D15 deficiency and its impact on autophagy and mitochondrial function. The research aims to identify new molecular targets for tauopathy treatment.