# NIH Reporter #5R01AG071868-05

Targeting Endosomal dysfunction as a new source of biomarkers for Alzheimer's disease

**Recipient:** Columbia University Health Sciences

**Award Amount:** $398,575.00
**Ceiling:** $398,575.00

**Awarded:** January 21, 2026

**Identifier:** 5R01AG071868-05

The project aims to identify biomarkers of endosomal trafficking defects associated with Alzheimer's disease, potentially supporting diagnosis and drug discovery.

### Description

NIH-funded project to develop biomarkers of endosomal dysfunction in Alzheimer's disease, investigating SORL1 mouse models, human neuronal cultures, biofluids, and exosomes.

[View original record](https://reporter.nih.gov/search/6baCKDp7ZEulW6R91k0BqA/project-details/11239773)