Award
NIH Reporter #5R35GM145237-05
Chemical Modifications in Regulatory Regions of DNA and RNA
Recipient
Utah State Higher Education System--University of Utah, Salt Lake City, UT
Award Amount
$462,000.00
Ceiling
$462,000.00
Awarded
June 03, 2026
Identifier
5R35GM145237-05
The award supports research on chemical modifications in DNA and RNA, developing sequencing methods to detect these modifications and studying their biological impact, particularly in gene regulation and response to oxidative stress.
Description
This project aims to understand chemical modifications in DNA and RNA bases by developing new chemical sequencing methods and studying the biological outcomes of these modifications. It focuses on oxidative stress, base modifications, gene regulation mechanisms, and utilizes nanopore sequencing technology.