Award
National Heart, Lung, and Blood Institute 5R01HL036024-36
Mechanistic role of membrane pore formation in lung-endothelial barrier failure due to blood-borne pathogens.
Recipient
Columbia University Health Sciences
Award Amount
$750,943.00
Ceiling
$750,943.00
Awarded
August 05, 2025
Identifier
5R01HL036024-36
NIH grant awarded to Columbia University Health Sciences to study lung-endothelial pore formation in sepsis-induced ARDS and evaluate potential therapies.
Description
This project aims to understand mechanisms underlying sepsis-induced ARDS caused by Pseudomonas aeruginosa bacteremia. It focuses on endothelial pore formation leading to barrier failure, evaluating pore-inhibiting strategies as potential therapies.