Award
Indiana University School of Dentistry 5R01AR080076-04
Uncovering the dual anabolic and anti-catabolic effects of Pyk2 inhibition on bone mass
Recipient
Indiana University Indianapolis, Department of Dentistry, United States
Award Amount
$445,734.00
Ceiling
$445,734.00
Awarded
August 04, 2025
Identifier
5R01AR080076-04
Research project funded by NIH to investigate Pyk2 inhibition effects on bone mass and potential osteoporosis treatment, conducted by Indiana University Indianapolis.
Description
This project aims to study the effects of Pyk2 inhibition on bone mass, with potential implications for osteoporosis treatment. The project involves multiple aims including examining Pyk2's role in bone remodeling, assessing bone preservation after sex steroid depletion, and testing a Pyk2 inhibitor in mice. The project is funded by NIH and involves collaboration with Indiana University Indianapolis.