Award
National Institute of Allergy and Infectious Diseases 1R21AI197039-01
Inhibiting CNS resident memory T cells driving neuroinflammation
Recipient
BENAROYA RESEARCH INST AT VIRGINIA MASON
Awarded
February 20, 2026
Identifier
1R21AI197039-01
Research project aimed at identifying novel inhibitory pathways and genes to inhibit maintenance of CNS resident memory T cells causing neuroinflammation, potentially leading to new multiple sclerosis therapies.
Description
This NIH grant supports research on the inhibition of CNS resident memory T cells to treat neuroinflammation, with a focus on multiple sclerosis. The project involves identifying molecular cues that inhibit TRM maintenance in the CNS during EAE, validating gene effects, and developing new MS therapies.