Award
National Heart, Lung, and Blood Institute 5F32HL172693-03
Cortical-hypothalamic control of the cardiovascular consequences of stress
Recipient
Colorado State University, Fort Collins, CO
Award Amount
$83,848.00
Ceiling
$83,848.00
Awarded
January 14, 2026
Identifier
5F32HL172693-03
The award supports research on how stress affects cardiovascular health differently in males and females by studying brain circuits involving the prefrontal cortex and hypothalamus. The project includes advanced neurophysiological and vascular function studies.
Description
This project investigates neural circuit-specific adaptations induced by stress that lead to differential cardiovascular susceptibility in males and females. It focuses on the role of the prefrontal cortex and hypothalamus in mediating the sexually divergent cardiovascular consequences of chronic stress, using viral-mediated circuit- and cell-type-specific slice electrophysiology and vascular reactivity testing.