Award

National Institute of Neurological Disorders and Stroke 1R01NS146509-01

Mechanism of alpha5 integrin contribution to Amyotrophic Lateral Sclerosis pathology

Recipient

Oregon Health & Science University

Award Amount

$615,186.00

Ceiling

$615,186.00

Awarded

April 01, 2026

Identifier

1R01NS146509-01

Research project awarded to Oregon Health & Science University to study the role of alpha5 integrin in ALS pathology and develop therapies, funded by NINDS with an award amount of $615,186.

Description

The project focuses on the role of α5 integrin in ALS pathology, involving genetic models and human iPSC-derived cellular systems to develop immunomodulatory therapies for ALS. The project is led by Dr. Bahareh Ajami at Oregon Health & Science University and funded by the National Institute of Neurological Disorders and Stroke (NINDS).

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