Award
National Eye Institute 5U01EY032973-04
First Aid Medicine to Treat Vesicant Induced Corneal Injury
Recipient
Ohio State University
Award Amount
$745,148.00
Ceiling
$745,148.00
Awarded
September 19, 2025
Identifier
5U01EY032973-04
NIH awarded $745,148 to Ohio State University to develop rhMG53 as a first-aid treatment for vesicant-induced corneal injuries, aiming for stockpiling and rapid deployment.
Description
This project aims to develop recombinant human MG53 (rhMG53) as a therapeutic agent for vesicant-induced corneal injuries, formulating it for ocular application as a first-aid medicine, and conducting validation studies in mouse and rabbit models to determine therapeutic efficacy and safety windows.