Award

NIH Reporter #5R00AG081536-04

Astrocyte-secreted proteins as modulators of neurodegeneration in Down Syndrome and Alzheimer's Disease

Recipient

National Institute on Aging (NIA)

Award Amount

$249,000.00

Ceiling

$249,000.00

Awarded

March 03, 2026

Identifier

5R00AG081536-04

Research project funded by the National Institute on Aging to study astrocyte-secreted proteins in neurodegeneration associated with Down Syndrome and Alzheimer's Disease, including proteomics training and therapeutic investigations.

Description

The project involves research on astrocyte-secreted proteins related to neurodegeneration in Down Syndrome and Alzheimer's Disease. The project includes training in mass spectrometry and proteomics analysis. The project aims to characterize changes in the astrocyte secretome and investigate the therapeutic potential of Pleiotrophin (Ptn).

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