Award

National Institute of General Medical Sciences 2R15GM134502-02

Assessing the Strength of Weak Ties

Recipient

South Dakota State University

Award Amount

$533,726.00

Ceiling

$533,726.00

Awarded

August 01, 2025

Identifier

2R15GM134502-02

This NIH grant funds research to upgrade the AQcalc web utility for identifying weak interactions in proteins and to develop rapid experimental assays to study these interactions, aiming to improve understanding of protein biophysics and related health applications.

Description

A grant to develop a comprehensive web utility (AQcalc upgrade) for identifying various weak interactions in protein structures and their complexes, and to develop rapid experimental assay systems to test the roles of these weak interactions. The research aims to enhance understanding of how weak interactions regulate macromolecular structure and function, with implications for health and disease.

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