# NIH Reporter #5F30CA298567-02

Molecular and Spatial Factors Defining Tumor-specific CD8 T Cell States in Cold Tumors

**Recipient:** Weill Medical College of Cornell University

**Award Amount:** $54,969.00
**Ceiling:** $54,969.00

**Awarded:** July 14, 2026

**Identifier:** 5F30CA298567-02

The project uses mouse tumor models and patient samples to study why CD8 T cells in cold tumors fail to differentiate and infiltrate tumors, with the goal of identifying factors associated with resistance or responsiveness to immunotherapy.

### Description

Research project investigating molecular and spatial factors that determine tumor-specific CD8 T cell states in cold tumors and mechanisms affecting tumor infiltration and response to immunotherapy.

[View original record](https://reporter.nih.gov/search/47CiHD0bJ0u2LtDABS0zbg/project-details/11379942)