Award
National Eye Institute 5R01EY030521-05
Predicting uveitis onset in children with juvenile idiopathic arthritis
Recipient
Cincinnati Children's Hospital Medical Center
Award Amount
$625,855.00
Ceiling
$625,855.00
Awarded
June 28, 2023
Identifier
5R01EY030521-05
This award funds research to identify biological and genetic markers to predict uveitis onset in children with juvenile idiopathic arthritis, aiming to improve early detection and intervention.
Description
Juvenile idiopathic arthritis-associated uveitis (JIA-U) is a chronic inflammatory eye disease affecting 20% of children with JIA, potentially leading to sight-threatening complications. The study aims to identify biomarkers in tears, genetic risk factors, and develop a risk estimator to predict uveitis onset, enabling early intervention.