Award
National Institute on Deafness and Other Communication Disorders 5R01DC014953-10
Transcriptional regulation of hair cell development in the hearing organ
Recipient
University of Iowa, Iowa City, IA, United States
Award Amount
$386,250.00
Ceiling
$386,250.00
Awarded
June 30, 2026
Identifier
5R01DC014953-10
Research project funded by NIH/NIDCD to study gene regulation in cochlear hair cell development and regeneration, aiming to improve treatments for hearing loss.
Description
The project aims to identify and characterize gene expression regulators essential for sensory cell development in the hearing organ, with the goal of advancing audiology and supporting efforts to induce regeneration of sensory cells in deaf subjects. The research focuses on the transcription factor TOX and its role in cochlear hair cell maturation, involving gene regulation mechanisms and potential therapeutic targets.