Award
NIH Reporter #5R01AI190301-02
Unraveling the molecular mechanisms of innate immune memory in humans
Recipient
University of Chicago, Chicago, IL, United States
Award Amount
$723,394.00
Ceiling
$723,394.00
Awarded
May 01, 2026
Identifier
5R01AI190301-02
NIH-funded research project investigating the epigenetic and genetic determinants of trained immunity in humans, focusing on molecular mechanisms and inter-individual variation.
Description
This research project aims to study epigenetic and genetic factors involved in innate immune memory using single-cell gene expression and chromatin accessibility profiling, in vitro and in vivo experiments, and QTL mapping to understand inter-individual variation.