Award
National Institute on Aging 5R01AG069227-05
Disambiguating natural aging from Alzheimer's disease through changes in oral neuromechanics
Recipient
University of Washington, Seattle, WA, United States
Award Amount
$1,267,577.00
Ceiling
$1,267,577.00
Awarded
June 12, 2024
Identifier
5R01AG069227-05
The project studies neural activity differences in oral neuromechanics between natural aging and Alzheimer's Disease using rhesus macaques to improve early diagnosis and treatment.
Description
This research aims to investigate changes in the cortical and biomechanical control of oromotor behavior in healthy aging versus pathological aging (Alzheimer's Disease). The study uses neurophysiological recordings from rhesus macaques to identify neural correlates of aging and AD-like impairments, with implications for early diagnosis and therapeutic interventions.