Award
National Institute of Allergy and Infectious Diseases 5R01AI173565-03
Protective antibody in streptococcal infection models
Recipient
New York Medical College, Valhalla, NY, United States
Award Amount
$591,266.00
Ceiling
$591,266.00
Awarded
December 09, 2025
Identifier
5R01AI173565-03
The award funds research to identify effective vaccine targets against group A streptococci by analyzing human serum and testing in mouse models, aiming to develop a universal GAS vaccine.
Description
This project aims to identify antigens that are effective targets of antibody-mediated immunity against group A streptococci (GAS) to provide global coverage against all GAS strains. The study involves analyzing pediatric and adult serum, testing in mouse models, and evaluating protection across four GAS disease models. The goal is to inform the development of a universal GAS vaccine.