Award
National Heart, Lung, and Blood Institute 5R35HL166661-04
Regulation of Progenitor Cell Plasticity in Lung Development and Disease-Repair
Recipient
Columbia University Health Sciences
Award Amount
$1,100,730.00
Ceiling
$1,100,730.00
Awarded
July 29, 2026
Identifier
5R35HL166661-04
This award supports research on lung progenitor cell plasticity to understand lung development, disease repair, and the origins of lung diseases such as COPD, using mouse models, organoids, and genetic-epidemiologic data.
Description
The project aims to investigate mechanisms of cell plasticity and their implications in lung development and disease. It involves studies using mouse models, organoid technology, and epidemiological data. The research addresses gaps in understanding lung stem cell regulation, intermediate cell states, and developmental origins of lung diseases.