Award
NIH Reporter #5U24CA270823-05
Center of Excellence for High Throughput Proteogenomic Characterization
Recipient
Not Specified
Award Amount
$1,087,619.00
Ceiling
$1,087,619.00
Awarded
June 23, 2026
Identifier
5U24CA270823-05
Award for a project to use advanced proteomics and metabolomics to study cancer mechanisms and develop personalized cancer vaccines.
Description
This project aims to employ state-of-the-art mass spectrometry-based proteomics and metabolomics technologies to systematically generate and analyze high-quality, comprehensive, and quantitative proteomic and metabolomic data. The goal is to identify signatures of cancer drivers, detect signaling network adaptations, and provide insights into post-translational modifications affecting cellular signaling, molecular complex formation, and protein stability. The project also focuses on analyzing tumor immune escape mechanisms and developing personalized cancer vaccines.