Award
National Institute of Allergy and Infectious Diseases 5K24AI166718-05
Studies on bacteriophages in respiratory diseases
Recipient
Stanford University
Award Amount
$160,218.00
Ceiling
$160,218.00
Awarded
June 19, 2026
Identifier
5K24AI166718-05
NIH grant awarded to Stanford University to study bacteriophages in respiratory diseases, focusing on antibiotic resistance and vaccine development.
Description
This project aims to support a patient-oriented research program focusing on bacteriophages' role in bacterial infections, particularly Pseudomonas aeruginosa (Pa). The research investigates how Pf phages contribute to antibiotic tolerance and resistance in biofilms, especially in cystic fibrosis patients. The study will also explore the protective role of Pf antibodies and their influence on clinical outcomes. The project involves developing vaccines targeting Pf phages, defining mechanisms of antibiotic tolerance and immune protection, and developing novel therapeutic strategies.