Award
National Cancer Institute 5U01CA297685-02
A non-invasive blood test for multi-cancer detection and determination of tissue of origin preceding overt cancer diagnosis
Recipient
University of Chicago
Award Amount
$676,491.00
Ceiling
$676,491.00
Awarded
April 21, 2026
Identifier
5U01CA297685-02
Award for developing a non-invasive blood test to detect multiple cancers early and determine tissue of origin using advanced genomic and machine learning techniques.
Description
This project focuses on developing a non-invasive blood test for early detection of multiple cancers using 5hmC signatures in plasma-derived cell-free DNA. It involves genome-wide analysis, machine learning models, and validation in prospectively collected samples.