Award
NIH Reporter #5R01HD105946-05
Regulation of axon guidance receptor trafficking in the developing mammalian central nervous system
Recipient
University of Pennsylvania, Philadelphia, PA, United States
Award Amount
$454,868.00
Ceiling
$454,868.00
Awarded
August 11, 2025
Identifier
5R01HD105946-05
Award for research on axon guidance receptor trafficking in the mammalian central nervous system to understand neuronal circuit assembly and promote nerve regeneration.
Description
This project investigates how Ndfip proteins control axon guidance by regulating Robo receptor trafficking and degradation, involving molecular, cellular, and in vivo studies to understand neuronal circuit assembly and potential therapeutic approaches for nerve regeneration.