Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5R01AR083437-03
Engineered cells as agents of arthritis therapy governed by artificial signaling
Recipient
Vanderbilt University
Award Amount
$399,680.00
Ceiling
$399,680.00
Awarded
July 24, 2026
Identifier
5R01AR083437-03
This award funds a bioengineering project at Vanderbilt University to create engineered cells that detect and respond to arthritis-related cartilage damage, aiming to develop a novel cell-based therapy for arthritis treatment.
Description
A project to develop a cell-based therapy to treat arthritis by programming joint-resident cells to respond to cartilage matrix degradation, using synthetic biology signaling systems to promote cartilage repair and reduce inflammation in arthritic joints.