Award
National Cancer Institute 3R01CA266617-05S1
Targeting Microenvironmental Signals in Myeloid Malignancies
Recipient
University of Rochester, Rochester, NY
Award Amount
$44,481.00
Ceiling
$44,481.00
Awarded
July 10, 2026
Identifier
3R01CA266617-05S1
Research project funded by the National Cancer Institute to study leukemia microenvironment interactions and develop new therapies for myeloid malignancies.
Description
This project investigates the role of leukemia-niche interactions in myeloid leukemogenesis, focusing on how osteoprogenitors support leukemia progression through taurine secretion. The study aims to determine if TauT expression is essential for disease progression in mouse models and primary human leukemias, potentially leading to new therapeutic strategies.